Specific weight management for
Prader-Willi Syndrome
Prader – Willi syndrome (PWS) is a rare genetic disorder caused by loss of function of a specific gene in the 15q11.2–q13 region of chromosome 15. One of the most challenging features of Prader-Willi syndrome is hyperphagia – an extreme and persistent sense of hunger that does not subside even after eating. This often leads to life-threatening obesity
Managing Obesity in
Prader‑Willi Syndrome:
The Promise of Beta‑Glucan
Obesity associated with PWS can result in several health complications, including Diabetes mellitus, heart failure, pulmonary hypertension, respiratory issues such as obstructive sleep apnea, hypoventilation, respiratory failure, chronic hypoxia from sleep-disordered breathing, hypotonia (decreased muscle tone), osteoporosis, high cholesterol, fatty liver, peripheral oedema, severe constipation, catastrophic gastric rupture from excessive eating, and behavioral problems. Respiratory and cardiovascular diseases are among the leading causes of death in individuals with Prader-Willi syndrome due to obesity. Therefore, effective body weight management is essential in the treatment and long – term care of people with PWS.
Conventional weight management approaches often provide limited success in individuals with PWS because of the hyperphagia associated with hypothalamic dysfunction. The hypothalamus plays a critical role in regulating appetite and satiety through pathways involving NPY/AgRP neurons. This is where beta–glucan may have significant therapeutic value.
Beta‑Glucan:
Nature’s Fiber That Fights Hunger and Fuels Gut Health
Beta-Glucans are specific soluble fibers. Research studies worldwide have proven that beta-glucan can help to suppress hunger and promote satiety through mechanisms involving appetite-regulating pathways in the hypothalamus.
As a soluble fiber, beta-glucan is not digested in the small intestine. Instead, it absorbs water to form a gel-like, viscous substance that slows down the rate at which food leaves the stomach and moves into the small intestine. It forms a thick, gel-like layer in the stomach and intestine, preventing the absorption of a good quantity of carbohydrate and fat into the body. Beta-glucan then reaches the large intestine and serves as a good feed for beneficial gut microbiota. Fermentation of beta-glucan by these microbiomes increases the production of hormones such as PYY and GLP1, which are involved in appetite regulation, satiety, and insulin metabolism. PYY and GLP1 hormones stimulate the NPY/AgRP cells in the hypothalamus to suppress appetite and promote satiety.
Beta‑Glucan:
Nature’s Fiber That Fights Hunger and Fuels Gut Health
Beta-Glucans are specific soluble fibers. Research studies worldwide have proven that beta-glucan can help to suppress hunger and promote satiety through mechanisms involving appetite-regulating pathways in the hypothalamus.
As a soluble fiber, beta-glucan is not digested in the small intestine. Instead, it absorbs water to form a gel-like, viscous substance that slows down the rate at which food leaves the stomach and moves into the small intestine. It forms a thick, gel-like layer in the stomach and intestine, preventing the absorption of a good quantity of carbohydrate and fat into the body. Beta-glucan then reaches the large intestine and serves as a good feed for beneficial gut microbiota. Fermentation of beta-glucan by these microbiomes increases the production of hormones such as PYY and GLP1, which are involved in appetite regulation, satiety, and insulin metabolism. PYY and GLP1 hormones stimulate the NPY/AgRP cells in the hypothalamus to suppress appetite and promote satiety.
High Beta‑Glucan Yavam for Weight & Metabolic Care.
Obesity associated with PWS can result in several health complications, including Diabetes mellitus, heart failure, pulmonary hypertension, respiratory issues such as obstructive sleep apnea, hypoventilation, respiratory failure, chronic hypoxia from sleep-disordered breathing, hypotonia (decreased muscle tone), osteoporosis, high cholesterol, fatty liver, peripheral oedema, severe constipation, catastrophic gastric rupture from excessive eating, and behavioral problems. Respiratory and cardiovascular diseases are among the leading causes of death in individuals with Prader-Willi syndrome due to obesity. Therefore, effective body weight management is essential in the treatment and long – term care of people with PWS.
Conventional weight management approaches often provide limited success in individuals with PWS because of the hyperphagia associated with hypothalamic dysfunction. The hypothalamus plays a critical role in regulating appetite and satiety through pathways involving NPY/AgRP neurons. This is where beta–glucan may have significant therapeutic value.
Stay Fuller, Healthier, and Stronger with Purified Yavam
In simple terms, beta-glucan is very effective in reducing body weight. Yavam is an ancient grain that belongs to the barley family and has the highest amount of beta-glucan among all grains. It is a superfood that contains a lot of vitamins, minerals, metals, and is rich in protein. Because of its high beta-glucan content, yavam should be purified in Triphala decoction to minimize side effects like bloating and acidity, and to fortify the health care qualities. Anyone can use purified yavam regularly from age 3 with the advice of a health care professional. When consuming high-molecular-weight purified yavam, appetite is controlled, satiety is promoted, slows down the emptying of the stomach and prevents the absorption of a good amount of carbohydrate and cholesterol from the food. As a result, body weight is successfully controlled. In addition to weight management, beta-glucan has many other health benefits: it lowers cholesterol, regulates blood sugar, reduces high blood pressure, boosts immunity, improves the gut microbiome, and increases the production of short-chain fatty acids. Research suggests it may improve brain function by supporting cognition and protecting against memory decline by reducing brain inflammation. Since 2008, we have been using purified yavam contains high molecular weight beta-glucan and individual ayurvedic medicine to treat severe obesity, diabetes, hypertension, hyperphagia, high cholesterol and fatty liver.
Stay Fuller, Healthier, and Stronger with Purified Yavam
In simple terms, beta-glucan is very effective in reducing body weight. Yavam is an ancient grain that belongs to the barley family and has the highest amount of beta-glucan among all grains. It is a superfood that contains a lot of vitamins, minerals, metals, and is rich in protein. Because of its high beta-glucan content, yavam should be purified in Triphala decoction to minimize side effects like bloating and acidity, and to fortify the health care qualities. Anyone can use purified yavam regularly from age 3 with the advice of a health care professional. When consuming high-molecular-weight purified yavam, appetite is controlled, satiety is promoted, slows down the emptying of the stomach and prevents the absorption of a good amount of carbohydrate and cholesterol from the food. As a result, body weight is successfully controlled. In addition to weight management, beta-glucan has many other health benefits: it lowers cholesterol, regulates blood sugar, reduces high blood pressure, boosts immunity, improves the gut microbiome, and increases the production of short-chain fatty acids. Research suggests it may improve brain function by supporting cognition and protecting against memory decline by reducing brain inflammation. Since 2008, we have been using purified yavam contains high molecular weight beta-glucan and individual ayurvedic medicine to treat severe obesity, diabetes, hypertension, hyperphagia, high cholesterol and fatty liver.
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